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张成

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一、基本信息

张成,博士,副教授

电子邮件:zhangcheng1988@whu.edu.cn

研究方向:

1.高分子材料的设计与改性

2.智能型纳米药物载体和响应型药物控释载体的制备

3.肿瘤靶向精准治疗研究

二、教育背景

2016.09–2019.12 武汉大学化学与分子科学学院,高分子化学与物理,理学博士

2012.09–2015.06 williamhill官网材料科学与工程学院,材料学,工学硕士

2008.09–2012.06 williamhill官网材料科学与工程学院,高分子材料与工程,工学学士

三、工作经历

2019.12至今 williamhill威廉希尔,博士后,副教授

四、科研项目

1.中国博士后科学基金面上资助,2021.01–2022.12,8万,在研,主持

2.省部共建生物催化与酶工程国家重点实验室开放课题资助,2021.12–2023.12,3万,在研,主持

3.williamhill官网青年基金,2022.01–2023.12,2万,在研,主持

4.国家自然科学基金委员会,面上项目,2019.01–2022.12,57万元,在研,参与

五、代表著作(#共同一作,*通讯作者)

1.Wang L, Qin W, Xu W, Huang F, Xie X, Wang F, Ma L*,Zhang C*. (2021) Bacteria-mediated tumor therapy via photothermally-programmed cytolysin A expression.Small17, 2102932.

2.Qin W, Wu Y, Hu Y, Dong Y, Hao T,Zhang C*. (2021) TPE-based peptide micelles for targeted tumor therapy and apoptosis monitoring.ACS Applied Bio Materials4, 1038−1044.

3.Zhang C,Qin WJ, Bai XF, Zhang XZ. (2020) Nanomaterials to relieve tumor hypoxia for enhanced photodynamic therapy.Nano Today35, 100960.

4.Zhang C,Peng SY, Hong S, et al. (2020) Biomimetic carbon monoxide nanogenerator ameliorates streptozotocin induced type 1 diabetes in mice.Biomaterials245, 119.

5.Wang SB,Zhang C,#et al. (2020) Near-infrared light responsive nanoreactor for simultaneous photothermal and anti-inflammation therapy of tumor.ACS Central Science6, 555–565.

6.Zhang C,et al. (2020) ZIF-8 integrated with glucose oxidase for glucose-responsive insulin delivery.Journal of Controlled Release320, 159–167.

7.Zhang C,Liu W, L, Bai X, F, et al, (20)A hybrid nanomaterial with NIR-induced heat and associated hydroxyl radical generation for synergistic tumor therapy.Biomaterials199, 1–9.

8.Zhang C,Zheng DW, Li CX, et al. (2019) Hydrogen gas improves photothermal therapy of tumor and restrains the relapse of distant dormant tumor.Biomaterials223, 119472.

9.Zhang C,Wang SB, Chen ZX, et al. (2019) A tungsten nitride-based degradable nanoplatform for dual-modal image-guided combinatorial chemo-photothermal therapy of tumors.Nanoscale11, 2027–2036.

10.Wang SB,Zhang C,#Chen Z, X, et al. (2019) A versatile carbon monoxide nanogenerator for enhanced tumor therapy and anti-inflammation.ACS Nano13, 5523–5532.

11.Wang S, BZhang C#, Liu X, H et al. (2019) A tungsten nitride-based O2self-sufficient nanoplatform for enhanced photodynamic therapy against hypoxic tumors.Advanced Therapeutics2, 1900012.

12.Hao TH,Zhang C,#et al, (2016) Effects of co-hard segments on the microstructure and properties thermoplastic poly(ether ester) elastomers.Journal of Applied Polymer Science133, 4337.

13.张成,纳米氧化锑锡增强聚碳酸酯的阻红外隔热性能,复合材料学报2015, 32, 365–369,

14.张成,催化剂对PBT/PTMG聚醚酯结构与性能影响,材料研究学报2014, 28, 781–786,

六、获奖

1.2020年获湖北省“楚天学者计划”楚天学子

2.2019年获得武汉大学“优秀共产党员”

3.2019年获得武汉大学“创新二等奖”

4.2014年获得williamhill官网“硕士研究生国家奖学金”

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